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Sperm quality and behavior of subpopulations.

Sperm quality and subpopulations behaviour.

The quality of the sperm from a semen sample does not depend, as was previously thought, on the individual quality of the semen, this depend the joint action of many sperm subpopulations.

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This conclusion, which is based on research carried out in recent decades by various research groups, has been corroborated by the joint work of researchers from the University of Valencia and the PROISER R + D, S.L.

The study on the sperm behaviour and their quality in samples of diverse species has been one of the main objectives of the research group by Dr. Carles Soler in the Departament of Celular biology, Functional Biology and Physical Anthropology of the Universitat de València for several decades. A line of research that has been linked to the approaches of I D I from the Valencian company PROISER, dedicated to the development of solutions for the diagnosis of semen samples. They have developed a revolutionary software to study the divers quantitative parameters of sperm samples.

As a result of the experience acquired, Dr. Carles Soler, as head of the University’s research group and as scientific director of PROISER, was invited to be the editor of two special issues in the prestigious journals Asian Journal of Andrology (2016) and Reproduction, Fertility and Development (2018), respectively, with morphometry and sperm kinetics.

The CASA systems (Computer Assisted Semen Analysis) developed by PROISER provides a databases for tens of thousands of sperm. The application of advanced statistical techniques of multivariate analysis (main components and cluster) from these databases have allowed to consolidate the concept of subpopulations.

Hitherto, has been thought that the behavior of sperm within an ejaculate was comparable to what happens in a marathon: many runners, in principle equivalent, competing for the goal that is the oocyte. Now, the verification mathematically coherent subpopulations points more or less organized team concept.

All of this is around about what happen the sperm in a female tract. Each spermatozoonfind many obstacules and barriers that help to select the best sperm. We can say that it is similar to chess. It would not make sense to spend the towers or even the king in the opening and the first dabbling, that’s what the pawns are for.

espermatozoideIn any case, we still do not know what the rules that the sperm through in the female genital tract. The essay by the Universitat de València and PROISER, are currently work for to find more solutions.

 

Referent in the reproduction area

In addition to the physiological conditions, these results should lead to the definition of changes in the strategies followed in assisted reproduction, both in their veterinary and human applications. This group of studies and the new perspectives that have consider turned the group of the Universitat de València and PROISER into world leaders.

This new points come in addition to other PROISER findings in the same area. It is this private company has been developing software and computer applications for more than a decade that help to do a successful seminal analysis.

In this way, PROISER continues to advance and placing Valencian talent at the top of the international ranking.

Merry Christmas and Happy New Year 2019

PROISER R+D strengthens its presence in Latin America, attending at the VII AVEMERE Congress

The Venezuelan Association of Reproductive Medicine (In spanish, AVEMERE), has organized the 7th edition of its congress, in Caracas. Many specialists has assisted from Japan, Argentina, Uruguay, and Mexico.

This meeting has been an opportunity to approximate the company to Venezuela. Our colleagues Almudena Garcia and Daznia Bompart have travelled to Caracas, to present our latests contributions to the Clinical Andrology, and to share the latests advances of Assisted Reproduction with all the attendants.

We would like to acknowledge the opportunity provided by the congress organization, and also all the support before and during the event.

The Scientific Manager of PROISER R+D participates in the pre-congress of the Reproduction group of AVEPA

Talk that Dr. Carles Soler will impart will focus on the importance of cell morphology in evaluation of semen quality.

 

The Association of Spanish Veterinarians specialists in small animals (AVEPA) organizes in Zaragoza, from 8 to 9 April, the XV Congress of Veterinary Specialties. It is a meeting point between different interest groups of AVEPA (ethology, ophthalmology, Oncology, dermatology, surgery and reproduction).

The study of the cell morphology is part of the analysis carried out to seminal sample to determine its quality. As well as the analysis of motility, it presents the same problems associated with the subjectivity of the analysis. “Large” or “round” are adjectives used in the classification of cell, being difficult to standardise these concepts. In addition, morphological analysis, so far, has involved, up to now, staining of cells and their associated processes: dehydration, fixing and mounting of histological preparations. This means that cells observed under the microscope have suffered alterations in its architecture.

The technique and the Trumorph® device will be presented at the Congress as a pioneering system in the morphological observation without alteration of the cellular structure, since it is based on the immobilization of cells by the application of pressure and heat on a slide and coverslip. The main objective is to standardize the way of preparation and evaluation of sperm samples, in a way that can be established a new objective and universal classification.

 Prof. Carles Soler talk will take place on Thursday 7 April, from 7pm to 8pm in the Veterinary Faculty of Zaragoza.